If you have a syringe, you could fill converters and eyedroppers that way (simply dip the nib into the bottle while tilting it a bit to get the pen going). The Write Fill Kit can be purchased from
Pear Tree Pens. You may also be able to find syringes at a local pharmacy. (I obtained syringes from my local vet.)
For other filling systems (like pistons, lever-fillers, vacumatics, aerometrics, and so forth), it's a bit trickier of course, but it can be done. It'll require both hands: one hand tilts the bottle and keeps it steady, while the other hand fills.
Examples: For pistons, hold the barrel close to the end, then rotate the piston mechanism with one's thumb (the movement similar to opening a water bottle, one handed). For levers, use one's thumb to flick the lever up and down. Aerometrics and vacumatics are relatively easy to fill one handed.
It'll take practice, but it's hardly unnerving. However, for the first couple of times, you may want to hold and angle the bottle against something that is steady, but allows a bit of give (like wet paper towels). With some practice, it becomes second nature. Hope that helps.