Shouldn't, I wouldn't think (but I'm no expert). If the part in question has no brassing at all then it should be completely covered in a layer of gold, which will not oxidize. (Is the underside of a GF clip also gilded? I assumed so but I don't actually know.) In order for water, air, or other reactive things to have any effect they have to get under the gold or get rid of the gold first.
It's certainly possible that the gold fill/plate process might not be complete, leaving some uncoated brass exposed somewhere, and oxidation could start there, but I think brassing as it's usually seen is almost always the result of physical wear. That could be daily use, years of intermittent use, overly enthusiastic cleaning or polishing, or whatever, but in all cases it means the gold layer is physically worn away.
If an old pen has been in a box or drawer for most of its life, I wouldn't expect to see any significant brassing.
But, it bears repeating that I'm no form of expert at all.