It would be very hard to isolate the effect of each filling system on the writing characteristics of the "51." You would need to test with the same nib, the same feed, same nib-feed adjustment, etc.
My gut feeling is that the other differences, the accidental differences of adjustment, would have more of an impact on how the pen writes. Similarly, I don't find any difference in the writing characteristics of the same cartridge/converter pen whether using cartridge or converter with the same ink.
The obvious "51" differences, cosmetics and "cool toy

" factor are enough reason for most of us on FPN to own and write with both.
Andy